Advanced Treatments for Breast Cancer: Targeted Therapies and Genetic Approaches to Slow Disease Progression

Pfizer offers breast cancer treatments specifically for advanced or metastatic stages, focusing on types that are hormone receptor-positive and HER2-negative. One key option combines targeted therapy with endocrine (hormone-blocking) treatments to inhibit cancer cell growth by interfering with the cell cycle. This combination has shown positive outcomes, particularly by slowing disease progression.

 In addition, Pfizer has a treatment for cases involving specific genetic mutations, which works by targeting the cancer cells’ DNA repair mechanism. This approach aims to damage cancer cells selectively while minimizing harm to healthy cells.

 These treatments are especially beneficial for metastatic breast cancer, providing options beyond standard therapies. Pfizer also supports access through assistance programs, making these treatments more accessible in certain cases.

The Brand Story
Founded in 2012 by visionary entrepreneur Anu Moturi, Kriya Medical Technologies is a dynamic force in the medical device industry. With a focus on bridging healthcare gaps through innovation, Kriya embodies a commitment to making healthcare accessible and affordable. The company’s essence is deeply rooted in its ability to balance affordability with quality, creating solutions that impact millions of lives across India and globally.

The Big Idea 
Kriya was born out of a personal drive to address the global disparity in healthcare access. Anu Moturi’s global experiences and the loss of her father to diabetes inspired her to build a world-class ecosystem for medical technology. The idea was simple yet powerful: to provide innovative, affordable, and high-quality medical devices that could transform diagnostic outcomes and patient care, particularly in underserved regions.

The Need Gap Kriya is Fulfilling
Kriya addresses a critical need in healthcare—the lack of affordable yet high-quality medical devices and diagnostic tools. The company's products, ranging from diabetes care solutions to molecular diagnostics, are designed to be both accessible and efficient, making healthcare solutions available to the masses. Kriya fills the gap in the market by offering innovative, cost-effective tools that can be deployed across urban and rural settings alike.

USPs/UBPs
Kriya’s unique selling propositions are its ability to combine innovation with affordability and its focus on creating patient-centric products. The company's molecular diagnostic kits, such as the KRIVIDA Novus and the Krivida Trivus Respi Panel, stand out for their quick turnaround times, precision, and ease of use. Additionally, Kriya’s diabetes management solutions enhance patient experiences by offering practical, user-friendly devices.

Vision–Mission–Philosophy
Kriya’s vision is encapsulated in its mission to “Touch a Billion Lives.” The company strives to improve healthcare access by developing affordable and innovative diagnostic solutions. This mission is driven by a philosophy of patient-centricity, affordability, and uncompromising quality. Kriya’s efforts are not only about developing products but about transforming the healthcare landscape and impacting the lives of patients globally.

Brand Leadership
Anu Moturi, Founder and CEO, is a trailblazer in the medical device sector, one of the few women leading in this industry. Her background in manufacturing and supply chain management, honed during her time at Ford Motor Company, has been instrumental in Kriya’s operational success. Her decade of experience in China also shaped her understanding of the medical device landscape and its global needs. Under her leadership, Kriya has grown into a world-class player in medical technology.

Innovative Initiatives and Future Milestones
Kriya has developed a wide array of products that have significantly impacted healthcare. Some of its flagship offerings include:

•   KRIVIDA Novus, an RT-PCR kit capable of detecting SARS-CoV-2, including the Omicron variant.
•    Krivida Trivus Respi Panel, which can simultaneously detect RSV, Influenza A & B, and SARS-CoV-2 in just 30 minutes.
•    Diabetes Care Solutions, including insulin syringes, pen needles, and safety lancets designed to improve patient care.

Kriya continues to expand globally, with recent achievements such as receiving the Medical Device Single Audit Program (MDSAP) certification, allowing it to enter new markets in the US, Canada, Brazil, Japan, and Australia. Upcoming milestones include further expansion of its product portfolio and deepening its global presence.

Honors/Awards
Kriya Medical Technologies has been recognized for its innovation, receiving the MDSAP certification, which validates its commitment to high regulatory standards across multiple global markets.

Leadership Quote
“My dream was to create a system for innovation and manufacturing that addresses the cost, quality, and accessibility of medtech solutions. I wanted to make patient-centric products that could truly impact lives,” says Anu Moturi, reflecting the passion behind Kriya’s mission.

Kriya Medical Technologies continues to push the boundaries of medical innovation, delivering products that are not just solutions but life-changing tools for patients worldwide.
 

Leadership at the Forefront: Driving Innovation and Excellence

Dr. Morepen's leadership is helmed by Anubhav Suri, CEO of Medical Devices, and Sushil Suri, Chairman and Managing Director. Under their guidance, the company has carved out a distinct space in the healthcare sector, particularly in diabetes management. Their leadership is driven by a commitment to innovation, quality, and customer satisfaction, which positions Dr. Morepen as a leader in the industry. Their vision of making advanced medical devices accessible to every household in India has been the cornerstone of the company's growth.

Innovative Breakthroughs and Milestones in Management

Over the past 25 years, Dr. Morepen has consistently pushed the boundaries of medical device manufacturing, ensuring that their products meet global standards. With a focus on in-house production, particularly at their ISO:13485 certified facility in Baddi, Himachal Pradesh, Dr. Morepen has minimized import dependence and maximized manufacturing efficiency. The company’s glucose meters have seen a doubling in sales over the last three years, and their glucose strips have surpassed a staggering 1.50 billion units sold. Additionally, the company's BP monitors have gained significant market traction, with over 1 million units sold last year. Dr. Morepen's relentless focus on innovation is evident in their development of next-generation products, including wearable sensors, which emphasize both functionality and aesthetics.

Purpose and Ambition: The Vision Behind Transformative Solutions

Dr. Morepen’s mission is rooted in the belief that every individual should have access to high-quality medical devices that enhance their health and well-being. This mission has guided their journey from a vision 25 years ago to a reality where they manufacture 100% of their products in India. Their vertically integrated production process, full backward integration, and continuous capacity expansion reflect a steadfast commitment to excellence. As Dr. Morepen expands its footprint internationally, entering markets in Southeast Asia and the Middle East, its vision remains clear: to lead in the medical devices category by delivering innovative, affordable, and high-quality healthcare solutions globally.

Leadership at the Forefront: Driving Innovation and Excellence

The Blue Circle Diabetes Foundation, India's largest patient-led NGO for diabetes, is driven by the visionary leadership of Nupur Lalvani. Drawing from her journey with type 1 diabetes, Nupur has turned her personal experience into a powerful advocacy platform. Her leadership is characterized by empathy, dedication, and a relentless commitment to enhancing the lives of those affected by diabetes. Nupur's strategic direction has significantly expanded the foundation’s reach and impact, transforming it into a leading voice in diabetes care across India. Recognized for her contributions, Nupur has been a key participant in global health forums, including the United Nations Multistakeholder Hearing on Universal Health Coverage in New York, in May 2023. Her patient-centered approach and focus on Universal Health Coverage (UHC) and non-communicable diseases (NCDs) continue to inspire and guide the foundation's initiatives.

Innovative Breakthroughs and Milestones in Management

The Blue Circle Diabetes Foundation has made significant strides in diabetes management and patient support. Their presence at major global health events, such as those organized by the WHO and the United Nations General Assembly, underscores their commitment to influencing diabetes care policies on an international level. A notable achievement is the foundation's award-winning Facebook group, Diabetes Support Network India, which provides a safe space for individuals with diabetes and their caregivers to connect and share experiences. The foundation’s diverse initiatives include awareness programs in schools, colleges, and corporations, support for underprivileged communities, and the Buddy Project Helpline—a peer support line focused on diabetes and mental health. Their educational efforts are extensive, producing blogs, videos, and over 200 patient-led online workshops. Additionally, Project Gaia addresses the unique challenges faced by women with diabetes, reinforcing the foundation's dedication to patient-led solutions.

Purpose and Ambition: The Vision Behind Transformative Solutions

The mission of the Blue Circle Diabetes Foundation is to educate, engage, and empower people with diabetes, equipping them with the tools and support needed to manage their condition effectively. Their vision is a world where individuals with diabetes have access to comprehensive care and can lead healthier, more fulfilling lives. This vision is rooted in the belief that informed and supported patients are better equipped to manage their health, reduce complications, and improve their quality of life. The foundation is committed to integrating diabetes management into broader healthcare initiatives and advocating for policies that prioritize diabetes care. Through building a supportive community, promoting proactive care, and collaborating with healthcare stakeholders, the Blue Circle Diabetes Foundation is driving lasting, positive change in the lives of those living with diabetes.
 

Diabetes Reversal Initiative

Sugar.fit offers a diabetes reversal program rooted in sustainability and long-term healing. Utilizing scientifically proven, evidence-based protocols, the program focuses on addressing the root causes of diabetes rather than relying on fad diets or extreme lifestyle changes. Under the guidance of world-class expert doctors, Sugar.fit provides a holistic approach to diabetes management.

Leadership at the Forefront: Driving Innovation and Excellence

Sugar.fit's innovative initiatives are spearheaded by co-founders Madan Somasundaram and Shivtosh Kumar. Madan, an alumnus of The Wharton School and Harvard Business School, brings a wealth of experience from his career as an investment banker at J.P. Morgan. He returned to India with a vision to revolutionize healthcare and founded Sugar.fit to develop a comprehensive solution to the diabetes epidemic that affects millions. Shivtosh Kumar, with over 14 years of experience in healthcare and technology, has been recognized as one of BW’s 40 under 40 in Healthcare. He has impacted over 40,000 users through his expertise in clinical and product research. Shivtosh’s strong background in product management and technology has been instrumental in leading Sugar.fit's innovative approach to diabetes care.

Innovative Breakthroughs and Milestones in Management

Sugar.fit has emerged as a groundbreaking force in the battle against Type 2 diabetes, especially in a country like India, often called the diabetes capital of the world. The company has revolutionized diabetes management by offering the first-of-its-kind personalized, technologically advanced, and evidence-based treatment options. This innovative approach has not only transformed individual lives but has also set new benchmarks in diabetes care.

One of Sugar.fit's most significant achievement is its pioneering use of Continuous Glucose Monitoring (CGM) devices. These devices provide real-time blood sugar data, allowing for precise and timely interventions. In addition, Sugar.fit conducts thorough diagnostic evaluations covering over 70+ health biomarkers, ensuring a comprehensive understanding of each user's health status.

The company has also made remarkable strides in personalized care. By assembling a team of top talents from across the country, Sugar.fit offers a tailored diabetes care plan that includes a personalized health coach and a dedicated diabetes doctor, both selected based on the user's language and dietary preferences. This approach ensures that the care provided is not only effective but also culturally and personally relevant.

Sugar.fit's innovative methodology doesn't just manage diabetes; it aims to reverse it. By equipping individuals with the right tools, knowledge, and support, Sugar.fit has empowered many to reclaim their health and live free from the constraints of diabetes. These advancements highlight Sugar.fit's role as a beacon of hope, leading the way in the next era of diabetes care.

Purpose and Ambition: The Vision Behind Transformative Solutions

Sugar.fit's mission is to empower millions of people with the knowledge, support, and science-backed products needed to effectively reverse and manage Type 2 diabetes. By leveraging personalized, technology-driven solutions, Sugar.fit is committed to transforming lives and enabling individuals to take control of their health. Looking to the future, Sugar.fit envisions a world where Type 2 diabetes is no longer a chronic condition. With a steadfast dedication to this mission, the company aims to make this vision a reality within the next decade, ensuring that everyone has access to the tools and resources needed to live free from the burdens of diabetes.

Leadership at the Forefront: Driving Innovation and Excellence

Fitterfly is spearheaded by a dynamic co-founding team of Dr. Arbinder Singal and Shailesh Gupta. This team, along with a group of seasoned professionals, is dedicated to revolutionizing diabetes management through a unique combination of lifestyle-based strategies and cutting-edge technology. Their approach complements traditional diabetes management methods by integrating medical expertise with technological advancements, positioning Fitterfly as a comprehensive platform for patients with diabetes and other metabolic diseases. The company’s leadership has successfully attracted $16 million in equity funding from prominent investors, including Amazon USA, Fireside Ventures India, and 9Unicorns Accelerator Fund, showcasing the confidence and trust these major players have in Fitterfly’s vision and execution.

Innovative Breakthroughs and Milestones in Management

Fitterfly has achieved remarkable success in the field of diabetes and other non-communicable disease (NCD) management, largely due to its innovative lifestyle management platform. This platform has introduced over 1,000 digital interventions, each carefully designed to address critical areas such as healthy eating, physical fitness, mental health, and disease knowledge. These interventions have yielded impressive outcomes, with 90% of people with diabetes who participated in the program experiencing better glycemic control, reflected in an average reduction of 1.6% units in HbA1c levels. Additionally, 30% of these individuals were able to reduce or completely stop their diabetes medications, and 80% achieved clinically significant weight loss, further highlighting the program’s efficacy.

Fitterfly’s commitment to innovation is evident in its latest advancements, including the development of a Personalized Glycemic Response (PGR) score. This tool guides patients in making informed food choices based on their unique glycemic responses, offering a personalized approach to dietary management. Additionally, Fitterfly has introduced “Jedi,” an AI-powered Diabetes Coach designed to assist patients with their daily needs, offering real-time support and guidance. 

Another groundbreaking feature is “Klik,” an AI-based tool that allows users to track their meals simply by taking food pictures, eliminating the need for manual data entry. These innovations have been recognized and showcased at prestigious conferences and meetings, solidifying Fitterfly’s status as a leader in digital diabetes management.

Purpose and Ambition: The Vision Behind Transformative Solutions

Fitterfly’s vision is bold and far-reaching: to positively impact the lives of a billion people suffering from chronic metabolic health conditions. To achieve this, Fitterfly has made it its mission to create a comprehensive ecosystem that seamlessly integrates advanced technology, evidence-based interventions, and personalized coaching. This ecosystem is designed to empower individuals to take control of their health conditions, providing them with the tools, knowledge, and support they need to manage their health effectively. Through this mission, Fitterfly aims to bring about a profound and lasting change in the way chronic metabolic conditions are managed, ultimately improving the quality of life for millions of people around the world.

Leadership at the Forefront: Driving Innovation and Excellence

Fitterfly is spearheaded by a dynamic co-founding team of Dr. Arbinder Singal and Shailesh Gupta. This team, along with a group of seasoned professionals, is dedicated to revolutionizing diabetes management through a unique combination of lifestyle-based strategies and cutting-edge technology. Their approach complements traditional diabetes management methods by integrating medical expertise with technological advancements, positioning Fitterfly as a comprehensive platform for patients with diabetes and other metabolic diseases. The company’s leadership has successfully attracted $16 million in equity funding from prominent investors, including Amazon USA, Fireside Ventures India, and 9Unicorns Accelerator Fund, showcasing the confidence and trust these major players have in Fitterfly’s vision and execution.

Innovative Breakthroughs and Milestones in Management

Fitterfly has achieved remarkable success in the field of diabetes and other non-communicable disease (NCD) management, largely due to its innovative lifestyle management platform. This platform has introduced over 1,000 digital interventions, each carefully designed to address critical areas such as healthy eating, physical fitness, mental health, and disease knowledge. These interventions have yielded impressive outcomes, with 90% of people with diabetes who participated in the program experiencing better glycemic control, reflected in an average reduction of 1.6% units in HbA1c levels. Additionally, 30% of these individuals were able to reduce or completely stop their diabetes medications, and 80% achieved clinically significant weight loss, further highlighting the program’s efficacy.

Fitterfly’s commitment to innovation is evident in its latest advancements, including the development of a Personalized Glycemic Response (PGR) score. This tool guides patients in making informed food choices based on their unique glycemic responses, offering a personalized approach to dietary management. Additionally, Fitterfly has introduced “Jedi,” an AI-powered Diabetes Coach designed to assist patients with their daily needs, offering real-time support and guidance. 

Another groundbreaking feature is “Klik,” an AI-based tool that allows users to track their meals simply by taking food pictures, eliminating the need for manual data entry. These innovations have been recognized and showcased at prestigious conferences and meetings, solidifying Fitterfly’s status as a leader in digital diabetes management.

Purpose and Ambition: The Vision Behind Transformative Solutions

Fitterfly’s vision is bold and far-reaching: to positively impact the lives of a billion people suffering from chronic metabolic health conditions. To achieve this, Fitterfly has made it its mission to create a comprehensive ecosystem that seamlessly integrates advanced technology, evidence-based interventions, and personalized coaching. This ecosystem is designed to empower individuals to take control of their health conditions, providing them with the tools, knowledge, and support they need to manage their health effectively. Through this mission, Fitterfly aims to bring about a profound and lasting change in the way chronic metabolic conditions are managed, ultimately improving the quality of life for millions of people around the world.

Leadership at the Forefront: Driving Innovation and Excellence

ARKRAY, founded in Japan in 1960, has been a leader in the global diabetes care market for over six decades. The company has consistently driven innovation under the guidance of visionary leadership, spearheading advancements in health and medical devices. With the establishment of its Indian subsidiary, ARKRAY Healthcare Pvt. Ltd., in Mumbai in 2007, ARKRAY extended its commitment to excellence in diabetes care to the Indian market. The leadership at ARKRAY has been pivotal in fostering a culture of innovation, resulting in the development of groundbreaking products and technologies that have set new standards in diabetes management.

Innovative Breakthroughs and Milestones in Management

ARKRAY has made significant contributions to the field of diabetes management, most notably by pioneering the world’s first Simple Blood Glucose Meter, EYETONE, in 1970, and the first Hemoglobin A1c analyzer in 1981. These innovations revolutionized how patients monitor their health and have become benchmarks in the industry.

In India, ARKRAY Healthcare has achieved remarkable success with its GLUCOCARD blood glucose devices, serving over 600,000 satisfied users. Additionally, ARKRAY's wide range of lab products, including HPLC HbA1c analyzers, reagents, and immune & serology markers, are utilized in over 20,000 laboratories across the country. The company’s state-of-the-art manufacturing facility in Surat and its R&D center in Pune further underscore its commitment to advancing diabetes care in India.

Purpose and Ambition: The Vision Behind Transformative Solutions

ARKRAY's mission is to contribute to global health and well-being through scientific advancement and the development of new technologies. This mission is reflected in the company’s dedication to improving diabetes care and other health services worldwide. ARKRAY Healthcare in India aligns with this vision by serving the domestic market and partnering with global agencies like WHO, USAID, and UNICEF to support screening programs in various countries. Through these efforts, ARKRAY continues to uphold its commitment to enhancing patient outcomes and advancing healthcare globally.

Leadership at the Forefront: Driving Innovation and Excellence

Mugdha Pradhan is the dynamic force behind iThrive, a health and wellness startup she founded in 2019. With a background as a nutritionist and a TEDx speaker, Mugdha has revolutionized the approach to chronic health conditions and lifestyle diseases by emphasizing Functional Nutrition and root cause analysis. Her visionary leadership, marked by determination and a nurturing spirit, has propelled iThrive into a realm of growth and success. Mugdha believes in the magic of multitasking, balancing her professional endeavors with personal passions like meme-making and grounding herself in nature.

“I created iThrive because I realized Functional Nutrition was the key to mending society's broken healthcare system and damaged frameworks. While conventional systems tell sick people that nothing can be done, Functional Nutrition shows that there is a solution, that we aren't doomed, and that the answer lies in what we eat.”

Innovative Breakthroughs and Milestones in Management

iThrive has made significant strides in diabetes management through its Functional Nutrition Approach, which focuses on addressing the root causes of Type 2 Diabetes Mellitus (T2DM) and prediabetes. A recent study published in Cureus demonstrated the effectiveness of iThrive's holistic intervention in improving glycemic and inflammatory markers among participants. Over a 90-day period, the study reported a substantial reduction in key indicators such as HbA1c (average 13.75% reduction), postprandial blood glucose (14.51% reduction), and postprandial serum insulin (34.31% reduction). These outcomes highlight iThrive's success in enhancing insulin sensitivity and reducing systemic inflammation through personalized dietary adjustments, supplementation, stress management, and environmental modifications.

By integrating these advancements, iThrive not only offers an innovative approach to diabetes management but also provides a sustainable path towards better health outcomes for individuals at risk of or living with diabetes. This research underscores the potential of Functional Nutrition in reversing chronic conditions, setting a new benchmark in the field of diabetes care.

Purpose and Ambition: The Vision Behind Transformative Solutions

iThrive is committed to reversing chronic health conditions and lifestyle diseases by identifying and addressing their root causes through a holistic Functional Nutrition approach. The organization empowers individuals to take control of their health through personalized interventions that promote lasting wellness. iThrive envisions creating healthier, happier, and lifestyle-disease-free communities worldwide every single day, by continuously advancing the science of Functional Nutrition and holistic healing.

Leadership at the Forefront: Driving Innovation and Excellence

Founded in 1972, the Research Society for the Study of Diabetes in India (RSSDI) is a cornerstone in the global diabetes care community. With over 11,500 members spanning 23 states, RSSDI is the largest society of diabetes physicians in India and ranks among the largest worldwide. The society's extensive network includes 21 state chapters and a collaborative partnership with the International Diabetes Federation, underscoring its commitment to advancing diabetes care and improving patient outcomes.

Innovative Breakthroughs and Milestones in Management

RSSDI's impactful initiatives and advancements reflect its dedication to enhancing diabetes management and services:

1. Public Awareness: RSSDI has successfully disseminated awareness messages to more than 1 million individuals, significantly raising public consciousness about diabetes and its management.

2. Prevention of Diabetic Foot Complications: The organization has screened over 100,000 people for diabetic foot complications, emphasizing its preventive approach to diabetes care.

3. Research Grants: RSSDI supports innovative research in diabetes through grants, fostering breakthroughs and advancements in the field.

4. Educational Outreach: Weekly YouTube live sessions are conducted to educate the public about diabetes, providing accessible and up-to-date information on managing the condition.

5. Conferences and Training: RSSDI organizes national and state conferences to keep medical practitioners informed about the latest developments in diabetes care and management.

Purpose and Ambition: The Vision Behind Transformative Solutions

The Research Society for the Study of Diabetes in India is driven by a mission to revolutionize diabetes care through comprehensive research, education, and advocacy. The organization’s goals include:

- Research: Conducting cutting-edge research and fostering innovation to enhance diabetes care.

- Education: Offering training and post-graduate studies for medical practitioners, ensuring they are well-equipped with the latest knowledge and skills.

- Awareness: Raising awareness about diabetes and the prevention of type 2 diabetes through various educational initiatives.

- Access to Care: Improving access to quality diabetes care for individuals across India.

- Cost-Effectiveness: Making diabetes care more affordable and accessible.

- Patient Data: Enhancing the quality and availability of patient data to drive better outcomes.

- Digital Tools: Utilizing digital technologies to support research and advance diabetes care.

- Public Health Policy: Contributing to the development of effective public health policies related to diabetes.

Through its multifaceted approach, RSSDI is committed to transforming diabetes care and fostering a healthier future for people living with diabetes in India.